Description

4-Chloro-6,7,8,9-Tetrahydrobenzofuro[3,2-D]Pyrimidine is a high-value heterocyclic building block and key synthetic intermediate. This compound is crucial for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D departments, agrochemical innovators, and advanced material scientists for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Agrochemical Development: Acts as a precursor in the creation of novel herbicides and fungicides with specific modes of action.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Material Science: Investigated as a building block for organic electronic materials and specialty polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	4-Chloro-6,7,8,9-Tetrahydrobenzofuro[3,2-D]Pyrimidine
CAS No.	1132690-77-7
Molecular Formula	C₁₀H₉ClN₂O
Molecular Weight	208.65 g/mol
Synonyms	4-Chloro-6,7,8,9-tetrahydro-5H-benzofuro[3,2-d]pyrimidine; 4-Chloro-5,6,7,8-tetrahydrobenzofuro[3,2-d]pyrimidine; 4-Chloro-6,7,8,9-tetrahydro-5H-[1]benzofuro[3,2-d]pyrimidine; Benzofuro[3,2-d]pyrimidine, 4-chloro-6,7,8,9-tetrahydro-; 1132690-77-7; AKOS006361889; ZINC000644019535
EINECS	Contact for details

Quality Control

Our 4-Chloro-6,7,8,9-Tetrahydrobenzofuro[3,2-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.