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6-Bromo-2,4-Dichloro-7-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine CAS NO 1131992-34-1


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CAS No.:1131992-34-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Bromo-2,4-Dichloro-7-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine is a high-value, multi-halogenated pyrrolopyrimidine derivative, serving as a critical advanced intermediate in modern organic synthesis. Its precise molecular architecture makes it indispensable for constructing complex heterocyclic scaffolds with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel kinase inhibitors, anticancer agents, and other small-molecule therapeutics.

Application

  • Pharmaceutical Intermediate: A key building block for the synthesis of potent and selective kinase inhibitors targeting various oncology pathways.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to explore new chemical entities.
  • Agrochemical Development: Serves as a precursor for creating novel active ingredients with potential herbicidal or fungicidal properties.
  • Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular signaling processes.
  • Organic Synthesis: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution for introducing complexity.

Basic Information

Product Name 6-Bromo-2,4-Dichloro-7-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No. 1131992-34-1
Molecular Formula C7H4BrCl2N3
Molecular Weight 281.94 g/mol
Synonyms 6-Bromo-2,4-dichloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 6-bromo-2,4-dichloro-7-methyl-; 6-Bromo-2,4-dichloro-7-methylpyrrolo[2,3-d]pyrimidine; 2,4-Dichloro-6-bromo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine; CAS 1131992-34-1
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Quality Control

Our 6-Bromo-2,4-Dichloro-7-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization using advanced techniques like HPLC, NMR, and LC-MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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