Description

6-Bromo-2,4-Dichloro-7H-Pyrrolo[2,3-D]Pyrimidine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its versatile halogenated structure, which serves as a key intermediate for constructing complex molecular architectures in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel kinase inhibitors, JAK/STAT inhibitors, and other small-molecule drug candidates targeting oncology and inflammatory diseases.
• Agrochemical Research: Used as a building block for developing new active ingredients in herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and labeled compounds for biochemical assays and diagnostic applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines for global clients.
• Academic Research: Utilized in university and institutional labs for methodological development in heterocyclic and medicinal chemistry.

Basic Information

Product Name	6-Bromo-2,4-Dichloro-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	1131992-30-7
Molecular Formula	C6H2BrCl2N3
Molecular Weight	282.91 g/mol
Synonyms	6-Bromo-2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine; 2,4-Dichloro-6-bromo-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 6-bromo-2,4-dichloro-; 6-Br-2,4-Cl2-7H-pyrrolo[2,3-d]pyrimidine; Bromo-dichloro-pyrrolopyrimidine; Pyrrolo[2,3-d]pyrimidine, 6-bromo-2,4-dichloro derivative
EINECS	Contact for details

Quality Control

Our 6-Bromo-2,4-Dichloro-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain integrity and traceability ensures reliable material for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.