Description

3-Chloro-5-Cyanobenzene-1-Sulfonyl Chloride is a high-purity, multi-functional chemical intermediate designed for advanced synthesis. Its unique structure, featuring both a reactive sulfonyl chloride group and a cyano substituent, makes it a critical building block for constructing complex molecules with precision. This compound is essential for research chemists and process developers in the pharmaceutical and agrochemical industries seeking to introduce sulfonamide or sulfonate functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel sulfonamide-based active pharmaceutical ingredients (APIs), including kinase inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the sulfonyl chloride moiety is incorporated for bioactivity.
• Material Science: Building block for creating specialized polymers, dyes, and liquid crystals that require specific electronic or steric properties.
• Chemical Research: Versatile reagent in organic synthesis for introducing the sulfonyl group, enabling further derivatization via the cyano and chloro functional groups.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	3-Chloro-5-Cyanobenzene-1-Sulfonyl Chloride
CAS No.	1131397-77-7
Molecular Formula	C7H3Cl2NO2S
Molecular Weight	236.07 g/mol
Synonyms	3-Chloro-5-cyanobenzenesulfonyl chloride; 5-Cyano-3-chlorobenzenesulfonyl chloride; 3-Chloro-5-cyanobenzene-1-sulfonyl chloride; 1-Chloro-3-cyano-5-(chlorosulfonyl)benzene; Benzenesulfonyl chloride, 3-chloro-5-cyano-; 3-Chloro-5-cyanophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-Cyanobenzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and IR spectroscopy, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.