Description

4-Chloroisoxazolo[5,4-D]Pyrimidine-3-Carboxylic Acid Ethyl Ester is a high-value heterocyclic building block and pharmaceutical intermediate of significant interest in modern organic synthesis. Its core structure is pivotal for constructing complex molecules with potential biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. Its unique scaffold offers a versatile platform for medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other enzymatic pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology & Proteomics: Employed as a specialized scaffold or linker in the design of chemical probes for studying biological processes and protein interactions.
• Academic & Contract Research: Essential for synthetic methodology development and exploring new chemical spaces in university and CRO (Contract Research Organization) laboratories.
• Material Science Exploration: Investigated as a monomer or precursor for creating novel organic electronic materials or polymers with specific functionalities.

Basic Information

Product Name	4-Chloroisoxazolo[5,4-D]Pyrimidine-3-Carboxylic Acid Ethyl Ester
CAS No.	1127366-79-3
Molecular Formula	C9H6ClN3O3
Molecular Weight	239.62 g/mol
Synonyms	Ethyl 4-chloroisoxazolo[5,4-d]pyrimidine-3-carboxylate; 4-Chloro-isoxazolo[5,4-d]pyrimidine-3-carboxylic acid ethyl ester; 1127366-79-3; 4-Chloro-3-ethoxycarbonylisoxazolo[5,4-d]pyrimidine; AI3-71431; AKOS040745424; CS-W013767; SCHEMBL21406449; ZINC000253859777
EINECS	Contact for details

Quality Control

Our 4-Chloroisoxazolo[5,4-D]Pyrimidine-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.