Description

(5-Oxo-2,3,5,6,7,8-Hexahydrocyclopenta[D][1,3]Thiazolo[3,2-A]Pyrimidin-3-Yl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate with a complex fused heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is essential for research and development chemists, process scale-up teams, and manufacturers in the pharmaceutical and biotechnology sectors seeking to develop new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds in academic and industrial R&D labs.
• Process Chemistry & Scale-Up: Used in the development and optimization of synthetic routes for the commercial production of target APIs, ensuring robust and reproducible processes.
• Bioconjugation & Probe Development: The acetic acid moiety allows for further functionalization, making it suitable for creating chemical probes, labeled compounds, or conjugates for biological studies.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the cGMP production of clinical trial materials and commercial drug substances.

Basic Information

Product Name	(5-Oxo-2,3,5,6,7,8-Hexahydrocyclopenta[D][1,3]Thiazolo[3,2-A]Pyrimidin-3-Yl)Acetic Acid
CAS No.	1125409-81-5
Molecular Formula	C11H12N2O3S
Molecular Weight	252.29 g/mol
Synonyms	2-(5-Oxo-2,3,5,6,7,8-hexahydrocyclopenta[4,5]thiazolo[3,2-a]pyrimidin-3-yl)acetic acid; Cyclopenta[4,5]thiazolo[3,2-a]pyrimidine-3-acetic acid, 5,6,7,8-tetrahydro-5-oxo-; (5-Oxo-5,6,7,8-tetrahydrocyclopenta[4,5]thiazolo[3,2-a]pyrimidin-3-yl)acetic acid; 1125409-81-5; Thiazolopyrimidine acetic acid derivative; Fused heterocyclic acetic acid intermediate.
EINECS	Contact for details

Quality Control

Our (5-Oxo-2,3,5,6,7,8-Hexahydrocyclopenta[D][1,3]Thiazolo[3,2-A]Pyrimidin-3-Yl)Acetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.