Description

4-(5-Bromopyrimidin-2-ylamino)benzoic acid is a high-purity, advanced pharmaceutical intermediate characterized by its bromopyrimidine and benzoic acid functional groups. This compound is essential for medicinal chemistry research and development, serving as a critical building block in the synthesis of targeted therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel small-molecule drugs, particularly kinase inhibitors and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic molecules.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex heterocyclic compounds in custom synthesis projects.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection products.

Basic Information

Product Name	4-(5-Bromopyrimidin-2-ylamino)benzoic Acid
CAS No.	1123515-90-1
Molecular Formula	C11H8BrN3O2
Molecular Weight	294.11 g/mol
Synonyms	4-[(5-Bromopyrimidin-2-yl)amino]benzoic acid; Benzoic acid, 4-[(5-bromo-2-pyrimidinyl)amino]-; 2-Amino-5-bromopyrimidin-4-yl benzoic acid; 4-(5-Bromo-2-pyrimidinylamino)benzoic acid; 1123515-90-1; 4-(5-Bromopyrimidin-2-ylamino)benzoic acid; 4-(5-Bromo-pyrimidin-2-ylamino)-benzoic acid
EINECS	Contact for details

Quality Control

Our 4-(5-Bromopyrimidin-2-ylamino)benzoic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.