Description

4-Chloro-5-Formyl-6-Thiomethylpyrimidine is a high-value pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its unique structure, featuring chloro, formyl, and thiomethyl functional groups, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other small-molecule drug candidates.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Used in the development of organic semiconductors, ligands for metal complexes, and advanced polymers.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	4-Chloro-5-Formyl-6-Thiomethylpyrimidine
CAS No.	1120214-80-3
Molecular Formula	C6H5ClN2OS
Molecular Weight	188.63 g/mol
Synonyms	4-Chloro-5-formyl-6-(methylthio)pyrimidine; 6-(Methylthio)-4-chloro-5-pyrimidinecarboxaldehyde; 4-Chloro-6-methylsulfanyl-pyrimidine-5-carbaldehyde; 4-Chloro-6-(methylthio)pyrimidine-5-carboxaldehyde; 4-Chloro-5-formyl-6-methylmercaptopyrimidine
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-5-Formyl-6-Thiomethylpyrimidine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) including purity (HPLC), identity (IR, NMR), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, prolonged exposure to light and air should be avoided. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.