Description

4-Hydroxy-n-{3-[Methyl(Naphthalen-2-Ylcarbonyl)Amino]Propyl}Quinazoline-2-Carboxamide is a sophisticated quinazoline-based organic compound designed for advanced research and development applications. This high-purity chemical building block is critical for medicinal chemistry programs, particularly in the synthesis of novel small molecule inhibitors targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D departments, biotechnology firms, and academic research institutions focused on oncology, kinase research, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies in drug discovery.
• Biochemical Assay Development: Employed as a reference standard or probe compound in high-throughput screening (HTS) and enzymatic assays.
• Academic & Contract Research: Essential for basic scientific research in organic synthesis, chemical biology, and pharmacology at universities and CROs.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the commercial-scale synthesis of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	4-Hydroxy-n-{3-[Methyl(Naphthalen-2-Ylcarbonyl)Amino]Propyl}Quinazoline-2-Carboxamide
CAS No.	1119504-09-4
Molecular Formula	C24H22N4O3
Molecular Weight	414.46 g/mol
Synonyms	4-Hydroxy-N-[3-[methyl(2-naphthoyl)amino]propyl]quinazoline-2-carboxamide; 4-Hydroxy-N-(3-{[methyl(2-naphthoyl)amino]propyl})quinazoline-2-carboxamide; 4-Hydroxy-N-(3-{[methyl(2-naphthoyl)amino]propyl})quinazoline-2-carboxamide; 4-Hydroxy-N-(3-{[methyl(2-naphthoyl)amino]propyl})quinazoline-2-carboxamide; 4-Hydroxy-N-(3-{[methyl(2-naphthoyl)amino]propyl})quinazoline-2-carboxamide; 4-Hydroxy-N-(3-{[methyl(2-naphthoyl)amino]propyl})quinazoline-2-carboxamide; 4-Hydroxy-N-(3-{[methyl(2-naphthoyl)amino]propyl})quinazoline-2-carboxamide; 4-Hydroxy-N-(3-{[methyl(2-naphthoyl)amino]propyl})quinazoline-2-carboxamide
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-n-{3-[Methyl(Naphthalen-2-Ylcarbonyl)Amino]Propyl}Quinazoline-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development projects with material that meets the stringent requirements for pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.