Description

4-Hydroxy-n-[3-(Propanoylamino)Propyl]Quinazoline-2-Carboxamide is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of heterocyclic compounds. This compound matters as a critical building block in the synthesis of novel, targeted therapeutic agents, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily needed by pharmaceutical R&D departments and fine chemical producers engaged in developing kinase inhibitors and other biologically active molecules for oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent kinase inhibitors and other targeted small-molecule drugs.
• Oncology Research: Serves as a core scaffold for developing novel anti-cancer compounds that interfere with specific cellular signaling pathways.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to optimize drug potency, selectivity, and pharmacokinetic properties.
• Biochemical Research: Employed as a reference standard or probe compound in enzymatic assays and biological target validation studies.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.

Basic Information

Product Name	4-Hydroxy-n-[3-(Propanoylamino)Propyl]Quinazoline-2-Carboxamide
CAS No.	1119503-66-0
Molecular Formula	C15H18N4O3
Molecular Weight	302.33 g/mol
Synonyms	4-Hydroxy-N-[3-(propionylamino)propyl]quinazoline-2-carboxamide; 2-Quinazolinecarboxamide, 4-hydroxy-N-[3-[(1-oxopropyl)amino]propyl]-; N-[3-(Propanoylamino)propyl]-4-hydroxyquinazoline-2-carboxamide; 4-Hydroxyquinazoline-2-carboxylic acid [3-(propionylamino)propyl]amide; Propanamide, N-[3-[[(4-hydroxy-2-quinazolinyl)carbonyl]amino]propyl]-
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-n-[3-(Propanoylamino)Propyl]Quinazoline-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.