Description

n-(2-Amino-4-Methylpentyl)Carbamic Acid 1,1-Dimethylethyl Ester is a high-purity, protected amino acid derivative serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive amine handle that is shielded by a Boc (tert-butoxycarbonyl) protecting group, enabling precise, multi-step synthetic sequences. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of novel peptides, active pharmaceutical ingredients (APIs), and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Protecting Group Strategy: The Boc (tert-butoxycarbonyl) group allows for orthogonal deprotection, facilitating the synthesis of complex molecules with multiple functional groups.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Bioconjugation: Serves as a precursor for creating linkers and functionalized molecules used in antibody-drug conjugates (ADCs) and other bioconjugates.
• Custom Synthesis: A valuable starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.

Basic Information

Product Name	n-(2-Amino-4-Methylpentyl)Carbamic Acid 1,1-Dimethylethyl Ester
CAS No.	1117693-62-5
Molecular Formula	C11H24N2O2
Molecular Weight	216.32 g/mol
Synonyms	Boc-Leucinol; (S)-2-((tert-Butoxycarbonyl)amino)-4-methylpentan-1-ol; tert-Butyl N-[(2S)-2-amino-4-methylpentyl]carbamate; N-Boc-L-leucinol; (S)-tert-Butyl (2-amino-4-methylpentyl)carbamate; Boc-L-Leucinol; (S)-2-(Boc-amino)-4-methyl-1-pentanol; Leucinol, N-Boc-
EINECS	Contact for details

Quality Control

Our n-(2-Amino-4-Methylpentyl)Carbamic Acid 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.