Description

2,6-Difluoro-4-Hydroxybenzaldehyde Oxime is a high-purity fluorinated aromatic oxime building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular tuning. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Ligand Precursor: Serves as a starting material for creating specialized chelating ligands used in catalysis and material science.
• Functional Material Research: Employed in academic and industrial R&D for constructing organic frameworks and polymers with specific electronic or optical properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis Projects: Supplied to contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical development programs.

Basic Information

Product Name	2,6-Difluoro-4-Hydroxybenzaldehyde Oxime
CAS No.	1116339-79-7
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	4-Hydroxy-2,6-difluorobenzaldehyde oxime; 2,6-Difluoro-4-hydroxybenzaldoxime; Benzaldehyde, 2,6-difluoro-4-hydroxy-, oxime; (2,6-Difluoro-4-hydroxyphenyl)methanone oxime
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-4-Hydroxybenzaldehyde Oxime is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.