Description

Ethyl 2-(4-Hydroxypiperidin-1-Yl)Pyrimidine-5-Carboxylate is a high-value pharmaceutical intermediate and versatile chemical building block. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical manufacturers, contract research organizations (CROs), and fine chemical suppliers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new bioactive molecules.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for the production of target APIs.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and target validation.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals for advanced material science applications.

Basic Information

Product Name	Ethyl 2-(4-Hydroxypiperidin-1-Yl)Pyrimidine-5-Carboxylate
CAS No.	1116339-70-8
Molecular Formula	C12H17N3O3
Molecular Weight	251.28 g/mol
Synonyms	Ethyl 2-(4-hydroxypiperidin-1-yl)pyrimidine-5-carboxylate; 2-(4-Hydroxy-1-piperidinyl)-5-pyrimidinecarboxylic acid ethyl ester; 5-Pyrimidinecarboxylic acid, 2-(4-hydroxy-1-piperidinyl)-, ethyl ester; 1-(5-(Ethoxycarbonyl)pyrimidin-2-yl)piperidin-4-ol; Ethyl 2-(4-hydroxypiperidin-1-yl)pyrimidine-5-carboxylate; 1116339-70-8
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Hydroxypiperidin-1-Yl)Pyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support development and commercial projects with material suitable for use under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.