Description

2-(4-Hydroxypiperidin-1-yl)pyrimidine-5-carboxylic acid is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and fine chemical production.

Application

• As a crucial pharmaceutical intermediate in the synthesis of kinase inhibitors and other targeted therapeutics.
• Utilized as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Employed in agrochemical research for the development of new active ingredients with specific biological activity.
• Serves as a building block for ligands and catalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Used in academic and industrial R&D for exploring new chemical spaces and novel heterocyclic compounds.

Basic Information

Product Name	2-(4-Hydroxypiperidin-1-yl)pyrimidine-5-carboxylic Acid
CAS No.	1116339-69-5
Molecular Formula	C10H13N3O3
Molecular Weight	223.23 g/mol
Synonyms	2-(4-Hydroxy-1-piperidinyl)-5-pyrimidinecarboxylic acid; 5-Pyrimidinecarboxylic acid, 2-(4-hydroxy-1-piperidinyl)-; 2-(4-Hydroxypiperidin-1-yl)pyrimidine-5-carboxylic acid; 2-(4-Hydroxy-piperidin-1-yl)-pyrimidine-5-carboxylic acid; 1116339-69-5; 2-(4-Hydroxy-1-piperidyl)pyrimidine-5-carboxylic acid; 2-(4-Hydroxypiperidino)pyrimidine-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(4-Hydroxypiperidin-1-yl)pyrimidine-5-carboxylic acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.