Description

2-Hydroxy-4-Phenylpyrimidine-5-Carboxylic Acid is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a hydroxyl group on the pyrimidine core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other biological pathways where the pyrimidine scaffold is relevant.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators that utilize heterocyclic chemistry.
• Material Science: Serves as a monomer or functional additive in the creation of specialized polymers, ligands for metal-organic frameworks (MOFs), or organic electronic materials.
• Chemical Synthesis: Acts as a versatile building block for creating more complex heterocyclic compounds, dyes, or photoactive materials in academic and industrial R&D.
• Bioconjugation & Probe Development: The carboxylic acid group allows for coupling to biomolecules, making it useful for creating diagnostic probes or biochemical tools.

Basic Information

Product Name	2-Hydroxy-4-Phenylpyrimidine-5-Carboxylic Acid
CAS No.	1116339-68-4
Molecular Formula	C11H8N2O3
Molecular Weight	216.19 g/mol
Synonyms	4-Phenyl-2-hydroxypyrimidine-5-carboxylic acid; 5-Carboxy-4-phenyl-2(1H)-pyrimidinone; 2(1H)-Pyrimidinone, 5-carboxy-4-phenyl-; 4-Phenyl-2-oxo-1,2-dihydropyrimidine-5-carboxylic acid; 2-Hydroxy-4-phenylpyrimidine-5-carboxylic acid; 5-Carboxy-4-phenyl-2-hydroxypyrimidine
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-4-Phenylpyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.