Description

tert-Butyl 2-(5-bromopyrimidin-2-yl)acetate is a high-purity brominated pyrimidine derivative, a crucial building block in modern organic synthesis. Its value lies in providing a protected carboxylic acid group and a reactive bromine atom, enabling precise molecular construction for advanced materials. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides by serving as a core heterocyclic scaffold.
• Material Science: Acts as a precursor for functionalized pyrimidine-based polymers or ligands for metal-organic frameworks (MOFs).
• Chemical Biology: Employed in the development of molecular probes and bioconjugates due to its reactive bromine site for cross-coupling reactions.
• Academic & R&D: Serves as a versatile starting material in methodological organic chemistry research and library synthesis for high-throughput screening.

Basic Information

Product Name	tert-Butyl 2-(5-Bromopyrimidin-2-yl)acetate
CAS No.	1114830-16-8
Molecular Formula	C10H13BrN2O2
Molecular Weight	273.13 g/mol
Synonyms	2-(5-Bromo-2-pyrimidinyl)acetic acid 1,1-dimethylethyl ester; tert-Butyl (5-bromopyrimidin-2-yl)acetate; Acetic acid, 2-(5-bromopyrimidin-2-yl)-, 1,1-dimethylethyl ester; 5-Bromo-2-pyrimidineacetic acid tert-butyl ester; 2-(5-Bromopyrimidin-2-yl)acetic acid tert-butyl ester; tert-Butyl 2-(5-bromopyrimidin-2-yl)acetate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(5-bromopyrimidin-2-yl)acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.