Description

2-Bromo-4-(Trifluoromethoxy)Benzaldehyde is a high-value, multi-functional aromatic aldehyde building block. This compound is critical for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences and specialty chemical sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for the development of fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Polymer Monomer: Acts as a monomer or co-monomer for introducing aromatic, halogenated, and fluorinated units into high-performance polymers.

Basic Information

Product Name	2-Bromo-4-(Trifluoromethoxy)Benzaldehyde
CAS No.	1114808-87-5
Molecular Formula	C8H4BrF3O2
Molecular Weight	269.02 g/mol
Synonyms	4-(Trifluoromethoxy)-2-bromobenzaldehyde; 2-Bromo-α,α,α-trifluoro-p-anisaldehyde; Benzaldehyde, 2-bromo-4-(trifluoromethoxy)-; 2-Bromo-4-trifluoromethoxybenzaldehyde; 2-Bromo-4-(trifluoromethoxy)benzaldehyde; 2-Br-4-TFMOBzAld
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(Trifluoromethoxy)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.