Description

2-Amino-6-{[(4-Methylphenyl)Thio]Methyl}Pyrimidin-4-Ol is a specialized pyrimidine derivative, a high-value intermediate in advanced organic synthesis. This compound matters for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique thioether-linked aromatic structure enables precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Material Science: Potential precursor for the synthesis of ligands in catalytic systems or functional organic materials.

Basic Information

Product Name	2-Amino-6-{[(4-Methylphenyl)Thio]Methyl}Pyrimidin-4-Ol
CAS No.	1114596-99-4
Molecular Formula	C12H13N3OS
Molecular Weight	247.32 g/mol
Synonyms	2-Amino-6-[(4-methylphenylthio)methyl]-4-pyrimidinol; 2-Amino-6-((p-tolylthio)methyl)pyrimidin-4-ol; 4(1H)-Pyrimidinol, 2-amino-6-[[(4-methylphenyl)thio]methyl]-; 2-Amino-6-[(4-methylphenyl)sulfanylmethyl]-1H-pyrimidin-4-one; 2-Amino-6-(p-tolylthiomethyl)pyrimidin-4-ol; 6-[(4-Methylphenylthio)methyl]-2-aminopyrimidin-4-ol; 2-Amino-6-(4-methylbenzylsulfanyl)pyrimidin-4-ol
EINECS	Contact for details

Quality Control

Our 2-Amino-6-{[(4-Methylphenyl)Thio]Methyl}Pyrimidin-4-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.