Description

3-Fluoro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is a high-value, multi-functional aromatic building block featuring both a formyl group and a protected boronic acid moiety. This compound is essential for facilitating advanced cross-coupling reactions, particularly in the synthesis of complex pharmaceutical intermediates and organic electronic materials. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries who require precise and reliable synthetic tools.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides that require fluorinated aromatic components.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Organic Light-Emitting Diodes (OLEDs): Employed in the creation of fluorinated electron-transport or emissive layer materials.
• Polymer Chemistry: Incorporated into polymer backbones to modify properties like solubility, thermal stability, and electronic characteristics.
• Chemical Biology Probes: Utilized for tagging and modifying biomolecules due to its reactive aldehyde and boronate ester functional groups.

Basic Information

Product Name	3-Fluoro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde
CAS No.	1112209-24-1
Molecular Formula	C13H16BFO3
Molecular Weight	250.08 g/mol
Synonyms	3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; (3-Formyl-5-fluorophenyl)boronic acid pinacol ester; 5-Formyl-3-fluorophenylboronic acid pinacol ester; 3-Fluoro-5-formylbenzeneboronic acid pinacol ester; 3-Fluoro-5-(pinacolatoboryl)benzaldehyde; CAS 1112209-24-1; 1112209-24-1
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.