Description

4-(3-Iodo-1H-Pyrazol-4-Yl)-2-(Methylthio)Pyrimidine is a high-value, heterocyclic organic compound featuring a pyrazole core linked to a substituted pyrimidine ring, serving as a critical synthetic intermediate. Its molecular architecture, particularly the iodine and methylthio functional groups, makes it an essential building block for constructing more complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical and agrochemical R&D laboratories for use in medicinal chemistry, specifically in the synthesis of novel active ingredients and as a key precursor in cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, particularly in oncology and antiviral research programs.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials and ligands for catalytic systems.
• Chemical Synthesis: Employed in Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions due to the reactive iodine substituent.
• Academic & Contract Research: Utilized in university and CRO settings for exploring new chemical entities and reaction methodologies.

Basic Information

Item	Details
Product Name	4-(3-Iodo-1H-Pyrazol-4-Yl)-2-(Methylthio)Pyrimidine
CAS No.	1111638-74-4
Molecular Formula	C8H7IN4S
Molecular Weight	318.14 g/mol
Synonyms	4-(3-Iodo-1H-pyrazol-4-yl)-2-(methylsulfanyl)pyrimidine; 2-(Methylthio)-4-(3-iodo-1H-pyrazol-4-yl)pyrimidine; 4-(3-Iodo-1H-pyrazol-4-yl)-2-methylthiopyrimidine; 1111638-74-4; AI3-63575; SCHEMBL21842427; ZINC000253899777; AKOS040759232
EINECS	Contact for details

Quality Control

Every batch of 4-(3-Iodo-1H-Pyrazol-4-Yl)-2-(Methylthio)Pyrimidine is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and mass spectrometry to verify identity, purity, and conformity. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications, ensuring batch-to-batch consistency and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.