Description

Pyrimidine, 4-(3-Iodo-1H-Pyrazol-4-Yl)- is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound is valued for its unique molecular architecture, which combines pyrimidine and iodopyrazole motifs, enabling precise molecular modifications. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for targeted therapies.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with specific modes of action.
• Chemical Biology Probe: Serves as a versatile scaffold for designing molecular probes to study biological pathways and protein interactions.
• Material Science Research: Employed in the synthesis of specialized organic electronic materials or metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Library Synthesis for HTS: A valuable building block for generating diverse compound libraries used in high-throughput screening (HTS) campaigns.

Basic Information

Item	Details
Product Name	Pyrimidine, 4-(3-Iodo-1H-Pyrazol-4-Yl)-
CAS No.	1111638-50-6
Molecular Formula	C7H5IN4
Molecular Weight	272.04 g/mol
Synonyms	4-(3-Iodo-1H-pyrazol-4-yl)pyrimidine; 4-(3-Iodo-1H-pyrazol-4-yl)pyrimidine; 3-Iodo-4-(pyrimidin-4-yl)-1H-pyrazole; 1H-Pyrazole, 3-iodo-4-(4-pyrimidinyl)-; 4-(3-Iodo-1H-pyrazol-4-yl)pyrimidine (CAS 1111638-50-6)
EINECS	Contact for details

Quality Control

Our Pyrimidine, 4-(3-Iodo-1H-Pyrazol-4-Yl)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.