Description

2-(2-(Methylthio)Pyrimidin-4-Yl)-3-Oxopropanenitrile is a high-purity, advanced pharmaceutical intermediate characterized by its pyrimidine core functionalized with a methylthio group and a reactive oxopropanenitrile moiety. This compound matters for its critical role as a versatile building block in the synthesis of complex, biologically active molecules, enabling precise molecular construction for research and development. It is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers focused on developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides that target specific enzymatic pathways.
• Chemical Research & Development: Serves as a versatile scaffold for heterocyclic chemistry and the creation of new chemical libraries for screening.
• Material Science: Potential building block for functional organic materials and ligands in catalytic systems.
• Contract Manufacturing: Supplied to CDMOs for the cGMP production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2-(2-(Methylthio)Pyrimidin-4-Yl)-3-Oxopropanenitrile
CAS No.	1111637-81-0
Molecular Formula	C9H7N3OS
Molecular Weight	205.24 g/mol
Synonyms	2-(2-Methylsulfanylpyrimidin-4-yl)-3-oxopropanenitrile; 3-Oxo-2-[2-(methylthio)-4-pyrimidinyl]propanenitrile; 2-(2-(Methylthio)-4-pyrimidinyl)-3-oxopropanenitrile; 2-(2-Methylthio-4-pyrimidinyl)-3-oxopropanenitrile; 2-(2-Methylmercaptopyrimidin-4-yl)-3-oxopropionitrile; Propanenitrile, 3-oxo-2-[2-(methylthio)-4-pyrimidinyl]-; CAS 1111637-81-0
EINECS	Contact for details

Quality Control

Our 2-(2-(Methylthio)Pyrimidin-4-Yl)-3-Oxopropanenitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring high standards, from research to cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.