Description

5-Bromo-4-Chloro-2-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine is a high-purity, heterocyclic building block of significant importance in modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate for the synthesis of novel kinase inhibitors and other biologically active molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of targeted cancer therapies, particularly protein kinase inhibitors.
• Agrochemical Research: Used in developing new active ingredients for crop protection products.
• Chemical Biology: Serves as a core scaffold for designing chemical probes to study enzyme function and cellular pathways.
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Custom Synthesis: Foundation for creating bespoke compounds in contract research and manufacturing (CRO/CMO) services.
• Academic Research: Utilized in universities and research institutes for medicinal chemistry programs and novel heterocycle exploration.

Basic Information

Product Name	5-Bromo-4-Chloro-2-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	1111237-76-3
Molecular Formula	C7H5BrClN3
Molecular Weight	246.49 g/mol
Synonyms	5-Bromo-4-chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-5-bromo-2-methyl-7H-pyrrolo[2,3-d]pyrimidine; 2-Methyl-5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 5-bromo-4-chloro-2-methyl-; BCPP; 5-Br-4-Cl-2-Me-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloro-2-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.