Description

5-(3,4-Difluorophenyl)Pyrimidin-2-Ol is a high-purity fluorinated pyrimidine derivative, a critical building block in modern organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the difluorophenyl moiety for enhanced bioactivity and stability.
• Material Science Research: Serves as a monomer or functional additive in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in the study of biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	5-(3,4-Difluorophenyl)Pyrimidin-2-Ol
CAS No.	1111108-31-6
Molecular Formula	C10H6F2N2O
Molecular Weight	208.17 g/mol
Synonyms	2-Pyrimidinol, 5-(3,4-difluorophenyl)-; 5-(3,4-Difluorophenyl)-2-hydroxypyrimidine; 5-(3,4-Difluorophenyl)pyrimidin-2(1H)-one; 5-(3,4-Difluorophenyl)-2(1H)-pyrimidinone; 1111108-31-6; 5-(3,4-Difluorophenyl)-2-pyrimidinol
EINECS	Contact for details

Quality Control

Our 5-(3,4-Difluorophenyl)Pyrimidin-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.