Description

5-(2,4-Difluorophenyl)Pyrimidin-2-Ol is a high-purity, fluorinated pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which is essential for constructing complex molecules with specific electronic and steric properties. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, leveraging the difluorophenyl moiety for enhanced biological activity and stability.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring fluorinated heterocyclic scaffolds.

Basic Information

Product Name	5-(2,4-Difluorophenyl)Pyrimidin-2-Ol
CAS No.	1111107-95-9
Molecular Formula	C10H6F2N2O
Molecular Weight	208.17 g/mol
Synonyms	2-Pyrimidinol, 5-(2,4-difluorophenyl)-; 5-(2,4-Difluorophenyl)-2-pyrimidinol; 5-(2,4-Difluorophenyl)pyrimidin-2(1H)-one; 2-Hydroxy-5-(2,4-difluorophenyl)pyrimidine; 5-(2,4-Difluorophenyl)-2(1H)-pyrimidinone; Difluorophenylpyrimidinol
EINECS	Contact for details

Quality Control

Our 5-(2,4-Difluorophenyl)Pyrimidin-2-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.