Description

5-[4-(Trifluoromethoxy)Phenyl]Pyrimidin-2-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its pyrimidine core and trifluoromethoxy-substituted phenyl ring. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily sought after by R&D teams and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products.
• Chemical Biology: Serves as a probe or scaffold in drug discovery and biochemical pathway studies.
• Material Science: Potential precursor for specialty polymers and advanced organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied for custom synthesis and process development projects.

Basic Information

Product Name	5-[4-(Trifluoromethoxy)Phenyl]Pyrimidin-2-Amine
CAS No.	1111105-03-3
Molecular Formula	C11H8F3N3O
Molecular Weight	255.20 g/mol
Synonyms	2-Amino-5-[4-(trifluoromethoxy)phenyl]pyrimidine; 5-(4-Trifluoromethoxyphenyl)pyrimidin-2-amine; 2-Pyrimidinamine, 5-[4-(trifluoromethoxy)phenyl]-; 1111105-03-3; 5-(4-(Trifluoromethoxy)phenyl)pyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our 5-[4-(Trifluoromethoxy)Phenyl]Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.