Description

2-Amino-5-(4-Trifluoromethylphenyl)Pyrimidine is a high-value, heterocyclic aromatic compound featuring a pyrimidine core substituted with an amino group and a trifluoromethylphenyl moiety. This specific molecular architecture makes it a critical pharmaceutical intermediate and building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the creation of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the biological activity of the pyrimidine scaffold.
• Material Science Research: Acts as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Amino-5-(4-Trifluoromethylphenyl)Pyrimidine
CAS No.	1111104-89-2
Molecular Formula	C11H8F3N3
Molecular Weight	239.20 g/mol
Synonyms	5-(4-(Trifluoromethyl)phenyl)pyrimidin-2-amine; 2-Pyrimidinamine, 5-[4-(trifluoromethyl)phenyl]-; 2-Amino-5-(4-trifluoromethylphenyl)pyrimidine; 2-Amino-5-(α,α,α-trifluoro-p-tolyl)pyrimidine; 5-(4-Trifluoromethylphenyl)-2-aminopyrimidine; 2-Amino-5-(4-trifluoromethyl-phenyl)-pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-(4-Trifluoromethylphenyl)Pyrimidine is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.