Description

2-Chloro-6,7-Dihydroquinazolin-8(5H)-One is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on kinase inhibitor libraries and other bioactive small molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides and pesticides with novel modes of action.
• Chemical Biology: Serves as a scaffold for designing molecular probes to study enzyme function and cellular pathways.
• Material Science: Potential building block for organic electronic materials and advanced polymers.
• Academic & Contract Research: Essential for medicinal chemistry programs and custom synthesis projects in academic and CRO settings.

Basic Information

Product Name	2-Chloro-6,7-Dihydroquinazolin-8(5H)-One
CAS No.	1105664-58-1
Molecular Formula	C8H7ClN2O
Molecular Weight	182.61 g/mol
Synonyms	2-Chloro-5,6,7,8-tetrahydroquinazolin-8-one; 2-Chloro-6,7-dihydro-8(5H)-quinazolinone; 8(5H)-Quinazolinone, 2-chloro-6,7-dihydro-; 2-Chloro-5,6,7,8-tetrahydroquinazolin-8(5H)-one; 1105664-58-1
EINECS	Contact for details

Quality Control

Our 2-Chloro-6,7-Dihydroquinazolin-8(5H)-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.