Description

4-(Piperazin-1-Yl)-6-(Pyrrolidin-1-Yl)Pyrimidine is a high-purity heterocyclic organic compound featuring a pyrimidine core substituted with piperazine and pyrrolidine moieties. This specific molecular architecture makes it a valuable and versatile pharmaceutical intermediate for the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the life sciences sector for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Kinase Inhibitor Research: Serves as a core scaffold for the development of small molecule kinase inhibitors due to its ability to interact with ATP-binding sites.
• Chemical Biology Probes: Used in medicinal chemistry to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry and heterocyclic compound reactivity.

Basic Information

Product Name	4-(Piperazin-1-Yl)-6-(Pyrrolidin-1-Yl)Pyrimidine
CAS No.	1105193-40-5
Molecular Formula	C12H19N5
Molecular Weight	233.31 g/mol
Synonyms	4-(1-Piperazinyl)-6-(1-pyrrolidinyl)pyrimidine; 6-(Pyrrolidin-1-yl)-4-(piperazin-1-yl)pyrimidine; 4-Piperazin-1-yl-6-pyrrolidin-1-yl-pyrimidine; 1105193-40-5; 4,6-Disubstituted Pyrimidine Derivative; Pyrimidine, 4-(1-piperazinyl)-6-(1-pyrrolidinyl)-
EINECS	Contact for details

Quality Control

Our 4-(Piperazin-1-Yl)-6-(Pyrrolidin-1-Yl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.