Description

Methyl 3-(6-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidin-5-Yl)Propanoate is a high-purity synthetic intermediate of significant importance in advanced organic synthesis. This compound matters because it serves as a versatile building block for constructing complex heterocyclic systems, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel dihydropyrimidinone (DHPM) derivatives, which are a privileged scaffold in medicinal chemistry with diverse biological activities.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that incorporate the pyrimidinone core structure.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes and tool compounds for studying enzyme mechanisms and biological pathways.
• Fine Chemical Manufacturing: Serves as a specialized building block for custom synthesis and the production of high-value, low-volume specialty chemicals.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chemical spaces in heterocyclic and combinatorial chemistry.

Basic Information

Item	Detail
Product Name	Methyl 3-(6-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidin-5-Yl)Propanoate
CAS No.	1105193-00-7
Molecular Formula	C9H12N2O4
Molecular Weight	212.20 g/mol
Synonyms	Methyl 3-(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)propanoate; 5-(2-Methoxy-2-oxoethyl)-6-methylpyrimidine-2,4(1H,3H)-dione; Methyl 3-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)propanoate; 6-Methyl-5-(2-methoxy-2-oxoethyl)dihydrouracil; DHPM Ester Derivative; Contact for details on additional synonyms.
EINECS	Contact for details

Quality Control

Our Methyl 3-(6-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidin-5-Yl)Propanoate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.