Description

3-(4-Fluorophenyl)-5-Methyl-2,4-Dioxo-2,3,4,5-Tetrahydro-1H-Pyrrolo[3,2-D]Pyrimidine-7-Carboxy is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyrimidine class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapies.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, particularly in oncology and antiviral research.
• Biochemical Research: Used as a reference standard or a core scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• API Development: Serves as a building block for the development of novel purine nucleoside analogue inhibitors and kinase inhibitors.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic pathways and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	3-(4-Fluorophenyl)-5-Methyl-2,4-Dioxo-2,3,4,5-Tetrahydro-1H-Pyrrolo[3,2-D]Pyrimidine-7-Carboxy
CAS No.	1105191-19-2
Molecular Formula	C14H10FN3O4
Molecular Weight	303.25 g/mol
Synonyms	7-Carboxy-3-(4-fluorophenyl)-5-methyl-1,5-dihydro-2H-pyrrolo[3,2-d]pyrimidine-2,4(3H)-dione; 3-(4-Fluorophenyl)-5-methyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid; 1105191-19-2; Pyrrolo[3,2-d]pyrimidine-7-carboxylic acid derivative; 4-Fluorophenyl pyrrolopyrimidine intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ validated analytical methods, including HPLC, NMR, and MS, to confirm chemical structure and meet the exacting standards required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.