Description

Methyl 2-Hydroxy-8-Methyl-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Carboxylate is a high-purity, synthetically valuable heterocyclic building block with the CAS registry number 1105189-76-1. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and complex molecular scaffolds. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, or as kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its complex pyridopyrimidine core for biological activity.
• Fine Chemical Synthesis: Acts as a versatile building block for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Material Science Precursor: Potential use in the development of organic semiconductors, ligands for catalysis, or advanced functional materials due to its conjugated structure.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms or protein-ligand interactions.

Basic Information

Product Name	Methyl 2-Hydroxy-8-Methyl-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Carboxylate
CAS No.	1105189-76-1
Molecular Formula	C11H10N2O4
Molecular Weight	234.21 g/mol
Synonyms	Methyl 2-hydroxy-8-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylate; 4H-Pyrido[1,2-a]pyrimidine-3-carboxylic acid, 2-hydroxy-8-methyl-4-oxo-, methyl ester; Methyl 2-hydroxy-8-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylate; 1105189-76-1; 2-Hydroxy-8-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Hydroxy-8-Methyl-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.