Description

5-Amino-1-tert-Butyl-1,5-Dihydro-4H-Pyrazolo[3,4-D]Pyrimidin-4-One is a high-purity, heterocyclic organic compound serving as a critical building block in advanced pharmaceutical research and development. This pyrazolopyrimidine derivative is valued for its role as a versatile synthetic intermediate in the creation of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of kinase inhibitors and other small-molecule drugs targeting various disease pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent and selective kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in vitro to study enzyme function and cellular signaling pathways relevant to disease mechanisms.
• Contract Manufacturing: Supplied to CDMOs for the cGMP production of active pharmaceutical ingredients (APIs) in clinical trial materials.
• Academic Research: Employed in university laboratories for the development of new synthetic methodologies and novel heterocyclic chemistry.

Basic Information

Product Name	5-Amino-1-tert-Butyl-1,5-Dihydro-4H-Pyrazolo[3,4-D]Pyrimidin-4-One
CAS No.	1105189-48-7
Molecular Formula	C9H13N5O
Molecular Weight	207.23 g/mol
Synonyms	1-tert-Butyl-5-amino-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; 5-Amino-1-(tert-butyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; 1-(1,1-Dimethylethyl)-5-amino-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; 5-Amino-1-tert-butyl-4H-pyrazolo[3,4-d]pyrimidin-4-one; tert-Butyl 5-aminopyrazolo[3,4-d]pyrimidin-1(5H)-yl ketone (tautomeric form); CAS 1105189-48-7
EINECS	Contact for details

Quality Control

Our 5-Amino-1-tert-Butyl-1,5-Dihydro-4H-Pyrazolo[3,4-D]Pyrimidin-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.