Description

4-Fluoro-2-(Trifluoromethoxy)Benzaldehyde is a high-value fluorinated aromatic aldehyde building block. This compound matters for its unique trifluoromethoxy and fluorine substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of advanced molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for advanced display technologies.
• Organic Electronics: Employed in the synthesis of novel organic semiconductors and electron-transport materials for OLEDs and photovoltaic cells.
• Advanced Material Research: Utilized as a specialty monomer or cross-linking agent in the development of high-performance polymers with specific thermal and chemical resistance properties.
• Chemical Synthesis Reagent: Acts as a versatile electrophile in palladium-catalyzed cross-coupling reactions, nucleophilic aromatic substitution, and reductive amination for complex molecule assembly.

Basic Information

Product Name	4-Fluoro-2-(Trifluoromethoxy)Benzaldehyde
CAS No.	1105060-20-5
Molecular Formula	C8H4F4O2
Molecular Weight	208.11 g/mol
Synonyms	4-Fluoro-2-(trifluoromethoxy)benzaldehyde; 2-Trifluoromethoxy-4-fluorobenzaldehyde; 4-Fluoro-α,α,α-trifluoro-o-anisaldehyde; Benzaldehyde, 4-fluoro-2-(trifluoromethoxy)-; 1105060-20-5; 4-Fluoro-2-trifluoromethoxybenzaldehyde; 2-(Trifluoromethoxy)-4-fluorobenzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(Trifluoromethoxy)Benzaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.