Description

Fmoc-o-Methyl-Dl-Tyrosine is a protected, non-natural amino acid derivative specifically engineered for solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers who require precise control over peptide structure and function, enabling the incorporation of modified tyrosine residues. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel therapeutic peptides, peptidomimetics, and research biochemicals where side-chain protection is essential.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the automated synthesis of complex peptides, particularly where tyrosine modification is required.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs, hormones, and diagnostic agents.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides or peptide-protein conjugates for biochemical assays.
• Academic & Industrial R&D: Essential for studying protein-protein interactions, enzyme mechanisms, and structure-activity relationships (SAR).
• Production of Peptidomimetics: Facilitates the creation of metabolically stable analogs of natural peptides for enhanced therapeutic properties.

Basic Information

Product Name	Fmoc-o-Methyl-Dl-Tyrosine
CAS No.	1105045-82-6
Molecular Formula	C26H25NO5
Molecular Weight	431.48 g/mol
Synonyms	Fmoc-O-Me-DL-Tyr-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-methyl-DL-tyrosine; Fmoc-O-Methyltyrosine; N-Fmoc-3-(4-methoxyphenyl)-DL-alanine; (RS)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-methoxyphenyl)propanoic acid; DL-Fmoc-O-methyltyrosine; Fmoc-DL-Tyr(Me)-OH
EINECS	Contact for details

Quality Control

Every batch of Fmoc-o-Methyl-Dl-Tyrosine is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency suitable for sensitive research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.