Description

3-Chloro-4-(1,1,2,3,3,3-hexafluoropropoxy)benzenamine is a specialized fluorinated aromatic amine intermediate of significant interest in advanced chemical synthesis. This compound matters for its unique structural features, combining a halogenated aromatic ring with a highly fluorinated alkoxy side chain, which imparts valuable properties for creating high-performance materials and active molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a critical intermediate for synthesizing fluorinated components used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Specialty Chemical Modification: Employed to introduce fluorinated aromatic amine functionalities into polymers, coatings, and specialty chemicals to alter surface properties, thermal stability, and chemical resistance.
• Research & Development: A valuable tool for academic and industrial research exploring structure-activity relationships (SAR) in medicinal chemistry and material science.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies engaged in custom synthesis and scale-up projects for client-specific molecules.

Basic Information

Product Name	3-Chloro-4-(1,1,2,3,3,3-hexafluoropropoxy)benzenamine
CAS No.	1100832-66-3
Molecular Formula	C9H6ClF6NO
Molecular Weight	293.59 g/mol
Synonyms	3-Chloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline; 4-Amino-2-chloro-1-(1,1,2,3,3,3-hexafluoropropoxy)benzene; 2-Chloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylamine; Benzenamine, 3-chloro-4-(1,1,2,3,3,3-hexafluoropropoxy)-; 3-Chloro-4-(hexafluoropropoxy)aniline; 1-(1,1,2,3,3,3-Hexafluoropropoxy)-3-chloro-4-aminobenzene; CAS 1100832-66-3
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(1,1,2,3,3,3-hexafluoropropoxy)benzenamine is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality ensures the material is suitable for demanding applications in pharmaceutical and advanced material research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.