Description

Cysteinylglycine Tfa is a protected dipeptide derivative, specifically the trifluoroacetyl (Tfa) form of the endogenous tripeptide glutathione metabolite. This compound is a crucial building block and intermediate in advanced pharmaceutical research and peptide synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for developing novel therapeutic agents and conducting metabolic studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex peptide-based drugs and prodrugs.
• Biochemical Research: Used as a standard or reagent in studies related to glutathione metabolism, oxidative stress, and redox biology.
• Peptide Synthesis: Serves as a protected dipeptide fragment in solid-phase and solution-phase peptide chemistry to construct larger, biologically active sequences.
• Protease & Enzyme Substrate/Analogue: Employed in enzymatic assays to study the activity and inhibition of enzymes like γ-glutamyl transpeptidase (GGT).
• Reference Standard: Used in analytical laboratories for method development and quality control (HPLC, LC-MS) of related pharmaceutical compounds.

Basic Information

Product Name	Cysteinylglycine Tfa
CAS No.	1100364-95-1
Molecular Formula	C8H13N3O4S
Molecular Weight	247.27 g/mol
Synonyms	N-(2-{[(2R)-2-Amino-3-mercaptopropyl]amino}-2-oxoethyl)trifluoroacetamide; L-Cysteinylglycine Trifluoroacetamide; Cys-Gly TFA; Cysteinyl-Glycine Trifluoroacetyl Derivative; H-Cys-Gly-NH-Tfa; (2R)-2-Amino-3-{[(2-{[(trifluoroacetyl)amino]methyl}-2-oxoethyl)amino]sulfanyl}propanoic Acid
EINECS	Contact for details

Quality Control

Our Cysteinylglycine Tfa is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, MS). We provide full traceability and a Certificate of Analysis (COA) with every shipment, ensuring compliance with research and cGMP-grade standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.