Description

2-Bromo-6-Methyl-4-(Trifluoromethyl)Aniline is a high-value, multi-functional aromatic amine building block characterized by its bromo, methyl, and trifluoromethyl substituents. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique halogenated and fluorinated structure imparts critical properties like metabolic stability and lipophilicity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for functionalized aromatic cores in electronic and display materials.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized, high-performance colorants and pigments.
• Organic Synthesis & Chemical Research: A versatile building block for academic and industrial research in medicinal and synthetic chemistry.

Basic Information

Product Name	2-Bromo-6-Methyl-4-(Trifluoromethyl)Aniline
CAS No.	1100212-65-4
Molecular Formula	C8H7BrF3N
Molecular Weight	254.05 g/mol
Synonyms	2-Bromo-6-methyl-4-(trifluoromethyl)benzenamine; 4-Amino-3-bromo-5-methylbenzotrifluoride; 3-Bromo-5-methyl-4-(trifluoromethyl)aniline; 2-Bromo-α,α,α-trifluoro-6-methyl-p-toluidine; 2-Bromo-6-methyl-4-trifluoromethylaniline; Benzenamine, 2-bromo-6-methyl-4-(trifluoromethyl)-; 2-Bromo-6-methyl-4-(trifluoromethyl)phenylamine
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Methyl-4-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.