Description

1-(2-Chloro-4-Fluorophenyl)Ethan-1-Amine is a high-purity fluorinated aromatic amine building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated structure enables precise molecular modifications. It is primarily sought after by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require fluorinated aromatic motifs for enhanced activity and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized as a scaffold for creating fluorescent tags and molecular probes for biochemical research.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1-(2-Chloro-4-Fluorophenyl)Ethan-1-Amine
CAS No.	1098070-11-1
Molecular Formula	C8H9ClFN
Molecular Weight	173.61 g/mol
Synonyms	1-(2-Chloro-4-fluorophenyl)ethanamine; α-Methyl-2-chloro-4-fluoroaniline; 1-Amino-1-(2-chloro-4-fluorophenyl)ethane; 2-Chloro-4-fluoro-α-methylbenzylamine; (2-Chloro-4-fluorophenyl)ethanamine; 1-(2-Chloro-4-fluorophenyl)ethylamine; 2-Chloro-4-fluoro-α-methylbenzylamine
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-4-Fluorophenyl)Ethan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.