Description

1-[2-Fluoro-4-(Trifluoromethyl)Phenyl]Ethan-1-Amine is a high-value fluorinated aromatic amine building block, essential for introducing specific steric and electronic properties into advanced molecular architectures. Its core value lies in enabling the synthesis of complex, high-performance compounds with enhanced stability and bioactivity. This intermediate is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in CNS and oncology research.
• Agrochemical Synthesis: Used in constructing advanced herbicides, fungicides, and insecticides where the fluorine and trifluoromethyl groups confer metabolic stability and lipophilicity.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Advanced Material Precursor: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and electronic materials.
• Chemical Research & Development: A versatile building block for medicinal chemistry and process chemistry in lead optimization and scale-up studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	1-[2-Fluoro-4-(Trifluoromethyl)Phenyl]Ethan-1-Amine
CAS No.	1098068-03-1
Molecular Formula	C9H7F4N
Molecular Weight	205.15 g/mol
Synonyms	1-(2-Fluoro-4-(trifluoromethyl)phenyl)ethanamine; α-Methyl-2-fluoro-4-(trifluoromethyl)benzylamine; 2-Fluoro-α-methyl-4-(trifluoromethyl)benzenemethanamine; 1-(2-Fluoro-4-trifluoromethylphenyl)ethylamine; 2-Fluoro-4-(trifluoromethyl)phenethylamine (common name variant); F-Phenyl-TFM Ethanamine; Benzenemethanamine, 2-fluoro-α-methyl-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 1-[2-Fluoro-4-(Trifluoromethyl)Phenyl]Ethan-1-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure the material meets your precise research or production requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality commitment supports compliance with relevant guidelines for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.