Description

4-Chloro-1-(4-Fluorophenyl)-6-Methyl-1H-Pyrazolo[3,4-D]Pyrimidine CAS NO 1097095-32-3 is a high-purity, heterocyclic organic compound belonging to the pyrazolopyrimidine class, serving as a critical advanced pharmaceutical intermediate. Its molecular structure makes it a valuable building block for medicinal chemistry research and the synthesis of targeted therapeutic agents. This compound is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel drug candidates, particularly in oncology and kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel active pharmaceutical ingredients (APIs), especially kinase inhibitors.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Serves as a reference standard or probe in biochemical assays to study specific enzymatic pathways and cellular processes.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create more complex, functionalized molecules for specialized applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Item	Details
Product Name	4-Chloro-1-(4-Fluorophenyl)-6-Methyl-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	1097095-32-3
Molecular Formula	C₁₂H₈ClFN₄
Molecular Weight	262.67 g/mol
Synonyms	4-Chloro-1-(4-fluorophenyl)-6-methyl-1H-pyrazolo[3,4-d]pyrimidine; 1-(4-Fluorophenyl)-4-chloro-6-methyl-1H-pyrazolo[3,4-d]pyrimidine; 4-Chloro-6-methyl-1-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine; Pyrazolo[3,4-d]pyrimidine, 4-chloro-1-(4-fluorophenyl)-6-methyl-; 1097095-32-3; 4-Chloro-1-(p-fluorophenyl)-6-methyl-1H-pyrazolo[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-1-(4-Fluorophenyl)-6-Methyl-1H-Pyrazolo[3,4-D]Pyrimidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized and released with a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material suitable for research and non-GMP development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.