Description

1-(2-Fluorophenyl)Pyrrolidin-3-Amine is a fluorinated pyrrolidine derivative, a high-value pharmaceutical intermediate prized for its role in constructing complex bioactive molecules. Its core value proposition lies in providing a versatile chiral amine scaffold for medicinal chemistry research and development, enabling the synthesis of targeted therapeutic agents. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to innovate new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to its fluorinated aromatic and chiral amine functionalities.
• Agrochemical Development: Serves as a precursor in the creation of advanced pesticides and herbicides, leveraging the bioactivity of the fluorophenyl-pyrrolidine structure.
• Ligand Synthesis: Employed in the development of chiral ligands for asymmetric catalysis, enhancing the efficiency of stereoselective synthetic routes.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Process Chemistry: Integrated into scalable synthetic routes for the production of active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	1-(2-Fluorophenyl)Pyrrolidin-3-Amine
CAS No.	1096836-33-7
Molecular Formula	C10H13FN2
Molecular Weight	180.22 g/mol
Synonyms	3-Amino-1-(2-fluorophenyl)pyrrolidine; 1-(2-Fluorophenyl)-3-pyrrolidinamine; 2-Fluorophenylpyrrolidin-3-amine; 1-(2-Fluorophenyl)pyrrolidin-3-ylamine; (2-Fluorophenyl)pyrrolidin-3-amine; 1-(2-Fluorophenyl)-3-aminopyrrolidine; 3-Amino-1-(o-fluorophenyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorophenyl)Pyrrolidin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to cGMP guidelines for advanced pharmaceutical applications, ensuring supply reliability and regulatory compliance for global markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.