Description

3-Bromo-4-Chloro-5-(Trifluoromethyl)Aniline is a high-value, multi-halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring bromo, chloro, and trifluoromethyl substituents, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and pesticides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic core.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing complex, high-performance colorants and functional dyes.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing biaryl systems.
• Fluorine Chemistry: The trifluoromethyl group makes it a valuable reagent for introducing fluorine atoms into target molecules to modulate lipophilicity and metabolic stability.

Basic Information

Product Name	3-Bromo-4-Chloro-5-(Trifluoromethyl)Aniline
CAS No.	1096698-03-1
Molecular Formula	C7H4BrClF3N
Molecular Weight	274.47 g/mol
Synonyms	3-Bromo-4-chloro-5-(trifluoromethyl)benzenamine; 2-Bromo-1-chloro-4-amino-5-(trifluoromethyl)benzene; 5-Amino-2-bromo-1-chloro-4-(trifluoromethyl)benzene; Benzenamine, 3-bromo-4-chloro-5-(trifluoromethyl)-; 3-Bromo-4-chloro-5-trifluoromethylaniline; 3-Bromo-4-chloro-alpha,alpha,α-trifluoro-m-toluidine
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Chloro-5-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.