Description

4-Chloro-3-Fluoro-2-Methyl-Phenylamine is a high-purity, halogenated aniline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which enables precise molecular modifications in the development of complex chemical entities. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where its structure contributes to biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for creating complex, light-fast azo dyes and high-performance pigments.
• Liquid Crystal & OLED Development: Employed in the synthesis of fluorinated components for electronic display technologies.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) for constructing complex biaryl systems.

Basic Information

Product Name	4-Chloro-3-Fluoro-2-Methyl-Phenylamine
CAS No.	1096113-25-5
Molecular Formula	C7H7ClFN
Molecular Weight	159.59 g/mol
Synonyms	2-Amino-4-chloro-3-fluoro-1-methylbenzene; 4-Chloro-3-fluoro-2-methylaniline; 2-Methyl-4-chloro-3-fluoroaniline; 1-Amino-2-methyl-4-chloro-3-fluorobenzene; Benzenamine, 4-chloro-3-fluoro-2-methyl-; (4-Chloro-3-fluoro-2-methylphenyl)amine
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Fluoro-2-Methyl-Phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.