Description

6,7,8,9-Tetrahydro-6-Methyl-8-Oxo-5H-Pyrimido-[4,5-E][1,4]Diazepine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1095822-63-1. This heterocyclic compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new pharmacologically active molecules.
• API Synthesis: Serves as a core scaffold for constructing fused heterocyclic systems present in potential therapeutic agents.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and chemical biology studies.

Basic Information

Product Name	6,7,8,9-Tetrahydro-6-Methyl-8-Oxo-5H-Pyrimido-[4,5-E][1,4]Diazepine-4-Carboxylic Acid
CAS No.	1095822-63-1
Molecular Formula	C10H10N4O3
Molecular Weight	234.21 g/mol
Synonyms	6-Methyl-8-oxo-5,6,7,8,9,10-hexahydropyrimido[4,5-e][1,4]diazepine-4-carboxylic acid; Pyrimido[4,5-e][1,4]diazepine-4-carboxylic acid, 6,7,8,9-tetrahydro-6-methyl-8-oxo-; 6-Methyl-8-oxo-5,6,7,8,9,10-hexahydro-pyrimido[4,5-e][1,4]diazepine-4-carboxylic acid; CAS 1095822-63-1; 6,7,8,9-Tetrahydro-6-methyl-8-oxo-5H-pyrimido[4,5-e][1,4]diazepine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6,7,8,9-Tetrahydro-6-Methyl-8-Oxo-5H-Pyrimido-[4,5-E][1,4]Diazepine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D and manufacturing. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.