Description

1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidine-4-Carboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly in kinase inhibitor research. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of targeted small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent kinase inhibitors for oncology and inflammatory disease research.
• Chemical Biology Probe Development: Used to create tool compounds for studying specific enzyme pathways and target validation.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical candidates.
• Academic Research: Employed in university laboratories for the exploration of new heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidine-4-Carboxylic Acid
CAS No.	1095822-30-2
Molecular Formula	C7H6N4O2
Molecular Weight	178.15 g/mol
Synonyms	1-Methyl-1H-pyrazolo[3,4-d]pyrimidine-4-carboxylic acid; 4-Pyrazolo[3,4-d]pyrimidinecarboxylic acid, 1-methyl-1H-; 1-Methyl-1H-pyrazolo[3,4-d]pyrimidine-4-carboxylate; 1-Methylpyrazolo[3,4-d]pyrimidine-4-carboxylic acid; 1-Methyl-1H-1,2,3-triazolo[4,5-d]pyrimidine-7-carboxylic acid (related structure); PPAC; CAS 1095822-30-2
EINECS	Contact for details

Quality Control

Our 1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The material is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.