Description

Methyl 6,7-Dihydro-6-Oxo-5H-Pyrrolo[2,3-D]Pyrimidine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a fused pyrrolopyrimidine core structure. This compound is a critical building block in the synthesis of novel, targeted therapeutic agents, offering researchers a reliable and scalable starting material. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in developing kinase inhibitors and other small molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a scaffold or reference standard in structure-activity relationship (SAR) studies and high-throughput screening (HTS) assays.
• API Development: Serves as a core structural component in the development of Active Pharmaceutical Ingredients (APIs) targeting specific enzymatic pathways.
• Medicinal Chemistry: Employed for the design and synthesis of novel heterocyclic compounds with potential therapeutic activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	Methyl 6,7-Dihydro-6-Oxo-5H-Pyrrolo[2,3-D]Pyrimidine-4-Carboxylate
CAS No.	1095822-24-4
Molecular Formula	C8H7N3O3
Molecular Weight	193.16 g/mol
Synonyms	Methyl 6-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine-4-carboxylate; 4-Carbomethoxy-5,6-dihydro-6-oxopyrrolo[2,3-d]pyrimidine; 6,7-Dihydro-6-oxo-5H-pyrrolo[2,3-d]pyrimidine-4-carboxylic acid methyl ester; Methyl 6-oxo-5,6-dihydropyrrolo[2,3-d]pyrimidine-4-carboxylate; Pyrrolo[2,3-d]pyrimidine-4-carboxylic acid, 6,7-dihydro-6-oxo-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 6,7-Dihydro-6-Oxo-5H-Pyrrolo[2,3-D]Pyrimidine-4-Carboxylate adheres to stringent internal quality standards, ensuring batch-to-batch consistency and high purity suitable for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles by HPLC are provided with every shipment. We support development projects requiring material produced under cGMP guidelines and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.