Description

1-tert-Butyl-1H,4H,5H-Pyrazolo[3,4-D]Pyrimidin-4-One CAS NO 1094377-59-9 is a high-purity, heterocyclic organic compound belonging to the pyrazolopyrimidinone class, serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. This product is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small molecule drugs.
• Drug Discovery Research: Used as a core scaffold for medicinal chemistry programs, enabling the exploration of new chemical entities for various disease targets.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Research: Potential use as a tool compound or probe for studying specific enzymatic pathways and biological mechanisms.
• Agrochemical Research: May be utilized in the development of new crop protection agents due to its heterocyclic structure.

Basic Information

Product Name	1-tert-Butyl-1H,4H,5H-Pyrazolo[3,4-D]Pyrimidin-4-One
CAS No.	1094377-59-9
Molecular Formula	C₉H₁₂N₄O
Molecular Weight	192.22 g/mol
Synonyms	1-tert-Butyl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one; 1-(tert-Butyl)-1,4,5,6-tetrahydropyrazolo[3,4-d]pyrimidin-4-one; 1-tert-Butyl-4,5-dihydropyrazolo[3,4-d]pyrimidin-4-one; 1-tert-Butyl-1,4,5,6-tetrahydro-pyrazolo[3,4-d]pyrimidin-4-one; 1094377-59-9; tert-Butyl pyrazolopyrimidinone; Pyrazolo[3,4-d]pyrimidin-4(5H)-one, 1-(1,1-dimethylethyl)-1,5-dihydro-
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl-1H,4H,5H-Pyrazolo[3,4-D]Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with cGMP guidelines for advanced pharmaceutical intermediates upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.