Description

2-[(4-Fluorobenzyl)Thio]-4,5-Dihydro-1H-Imidazole Hydrochloride is a specialized organic compound featuring a fluorinated benzylthio group attached to a dihydroimidazole core, presented as a hydrochloride salt. This structure makes it a valuable pharmacological intermediate and building block in medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those targeting neurological or cardiovascular pathways.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, or pesticides with enhanced efficacy.
• Chemical Biology Probe: Utilized in biochemical assays to study enzyme inhibition or receptor-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Used in university and institutional labs for fundamental organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	2-[(4-Fluorobenzyl)Thio]-4,5-Dihydro-1H-Imidazole Hydrochloride
CAS No.	1094031-65-8
Molecular Formula	C10H11FN2S • HCl
Molecular Weight	246.73 g/mol
Synonyms	2-[(4-Fluorophenyl)methyl]sulfanyl-4,5-dihydro-1H-imidazole hydrochloride; 4,5-Dihydro-2-[[(4-fluorophenyl)methyl]thio]-1H-imidazole hydrochloride; 1H-Imidazole, 4,5-dihydro-2-[[(4-fluorophenyl)methyl]thio]-, hydrochloride (1:1); 2-(4-Fluorobenzylthio)-2-imidazoline hydrochloride; 2-(4-Fluorobenzylthio)-4,5-dihydroimidazole HCl; (4,5-Dihydro-1H-imidazol-2-ylsulfanylmethyl)-fluorobenzene hydrochloride
EINECS	Contact for details

Quality Control

Our 2-[(4-Fluorobenzyl)Thio]-4,5-Dihydro-1H-Imidazole Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.