Description

2-Chloro-5-Iodo-n-Methylpyrimidin-4-Amine CAS NO 1093847-70-1 is a halogenated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents, makes it a versatile intermediate for constructing complex molecules with high precision. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of targeted small-molecule drugs, including kinase inhibitors and antiviral agents.
• Agrochemical Research: Used as a precursor in the development of new herbicides, fungicides, and pesticides with specific modes of action.
• Chemical Biology: Serves as a valuable probe or labeling reagent in biochemical studies and diagnostic assay development.
• Material Science: Employed in the synthesis of specialty polymers and liquid crystals where the pyrimidine core imparts specific electronic properties.
• Cross-Coupling Reactions: The iodo and chloro groups make it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.

Basic Information

Product Name	2-Chloro-5-Iodo-n-Methylpyrimidin-4-Amine
CAS No.	1093847-70-1
Molecular Formula	C5H5ClIN3
Molecular Weight	269.47 g/mol
Synonyms	4-Amino-2-chloro-5-iodo-N-methylpyrimidine; 2-Chloro-5-iodo-4-(methylamino)pyrimidine; 2-Chloro-5-iodo-N-methylpyrimidin-4-amine; 1093847-70-1; 4-Pyrimidinamine, 2-chloro-5-iodo-N-methyl-
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Iodo-n-Methylpyrimidin-4-Amine is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.